Practical and Efficient Method for α-Sialylation with an Azide Sialyl Donor Using a Microreactor.
Practical and Efficient Method for α-Sialylation with an Azide Sialyl Donor Using a Microreactor.
复制标题
使用微反应器与叠氮唾液酸供体进行 α-唾液酸化的实用且有效的方法。
DOI：
10.1080/07328303.2014.880116
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发表时间：
2014
影响因子：
1
通讯作者：
K.
中科院分区：
文献类型：
--
作者：
Uchinashi;Y.;Tanaka;K.;Manabe;Y.;Fujimoto;Y.;Fukase;K.
Efficient α-sialylation with a C5 azide sialyl donor was investigated under microfluidic conditions using a microreactor composed of a Comet X-01 micromixer and a tube reactor. Precise temperature control realized excellent α-selectivity, and Siaα(2,6)Gal, Siaα(2,3)Gal, and Siaα(2,9)Sia disaccharides were obtained in moderate to good yields.
