STRUCTURE OF DESACYLSAPONINS OBTAINED FROM THE BARK OF QUILLAJA-SAPONARIA
STRUCTURE OF DESACYLSAPONINS OBTAINED FROM THE BARK OF QUILLAJA-SAPONARIA
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DOI：
10.1016/s0031-9422(00)81518-6
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发表时间：
1987-01-01
期刊：
影响因子：
3.8
通讯作者：
OAKENFUL, DG
中科院分区：
文献类型：
--
作者：
HIGUCHI, R;TOKIMITSU, Y;OAKENFUL, DG
从皂皮树（Quillaja saponaria）的树皮中分离得到一种三萜皂苷混合物（即皂皮树皂苷），经弱碱处理后得到两种主要的脱酰基皂苷。基于化学和光谱证据，它们被确定为3-O-β- D-吡喃半乳糖基-（1 →）2）-[β- D-吡喃木糖基-（1 → D）3）]-β- D-吡喃葡萄糖醛酸基皂皮酸28-O-β- D-阿皮奥呋喃糖基-（1 →3）-β- D-吡喃木糖基-（1 → D）4）-α- L-吡喃鼠李糖基-（1 →2）-β- D-岩藻吡喃糖苷和28-O-β- D-阿皮奥呋喃糖基-（1 →3）-β- D-吡喃木糖基-（1 → D）4）-[b-D-吡喃葡萄糖基]-（1 →3）]-α- L-吡喃鼠李糖基-（1 →2）-β- D-吡喃岩藻糖苷重氮甲烷降解从3，28-O-双糖苷中选择性地生成28-O-糖苷是一种有效的结构鉴定方法。
A triterpenoid saponin mixture (so-called quillajasaponin) obtained from the bark of Quillaja saponaria was treated with weak alkali and two major desacylsaponins were isolated. On the basis of chemical and spectral evidence, they were determined as 3-O-.beta.-D-galactopyranosyl-(1 .fwdarw. 2)-[.beta.-D-xylopyranosyl-(1 .fwdarw. 3)]-.beta.-D-glucuronopyranosyl quillaic acid 28-O-.beta.-D-apiofuranosyl-(1 .fwdarw. 3)-.beta.-D-xylopyranosyl-(1 .fwdarw. 4)-.alpha.-L-rhamnopyranosyl-(1 .fwdarw. 2)-.beta.-D-fucopyranoside and 28-O-.beta.-D-apiofuranosyl-(1 .fwdarw. 3)-.beta.-D-xylopyranosyl-(1 .fwdarw. 4)-[b-D-glucopyranosyl-(1 .fwdarw. 3)]-.alpha.-L-rhamnopyranosyl-(1 .fwdarw. 2)-.beta.-D-fucopyranoside. Diazomethane degradation providing selectively the 28-O-glycoside from the 3,28-O-bisglycoside was a useful method for the structure elucidation.