The relationship of disease severity, health beliefs and medication adherence among HIV patients
The relationship of disease severity, health beliefs and medication adherence among HIV patients
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DOI：
10.1080/09540120050123783
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发表时间：
2000-08-01
影响因子：
1.7
通讯作者：
Woodward, C
中科院分区：
文献类型：
--
作者：
Gao, X;Nau, DP;Woodward, C
目的是调查艾滋病毒/艾滋病患者疾病严重程度、健康信念和药物依从性之间的关系。对处于 HIV/AIDS 三个不同阶段（CDC 临床类别 A、B、C）的 72 名患者进行了一项调查。多变量分析显示，患者对艾滋病毒/艾滋病严重程度的看法或对三个疾病阶段治疗的益处和障碍的看法没有显着差异。然而，与无症状患者（A 期）相比，病情最严重的患者（C 期）认为，如果不按处方服药，出现并发症的风险更高 (p = 0.01)。此外，与 A 期患者相比，B 期和 C 期患者对药物的依从性更高 (p = 0. 007)。最后，感知的易感性不作为与药物依从性呈正相关（p = 0. 005），而遵循医生指示的困难与患者的药物依从性呈负相关（p = 0. 009）。总之，患者的疾病经历与他们对如果不坚持用药就有可能出现并发症的信念有关。与先前没有并发症的患者相比，经历过更多并发症的患者认为药物不依从性与艾滋病相关并发症之间的关系更强，并且也更能坚持其药物治疗方案。
The objective was to investigate the relationship of disease severity, health beliefs and medication adherence among HIV/AIDS patients. A survey was administered to 72 patients in three different stages of HIV/AIDS (CDC clinical categories A, B, C). Multivariate analyses revealed that there were no significant differences in patients' perceptions of the severity of HIV/AIDS or perceptions of the benefits and barriers for the treatment across three disease stages. However, the most severely ill patients (tn stage C) perceived a higher risk of complications if they did not take their medicine as prescribed compared to asymptomatic patients (stage A) (p = 0.01). Also, patients in stages B and C were more adherent to their medications compared to patients in stage A (p = 0. 007). Finally, perceived susceptibility inaction was positively related to medication adherence (p = 0. 005) and difficulty in following doctors' instructions was negatively related to patients' medication adherence (p = 0. 009). In conclusion, patients' illness experiences are associated with their beliefs about the chances of developing complications if they do not adhere to their medications. Patients who have experienced more complications perceive a stronger relationship between medication non-adherence and AIDS-related complications, and are also more adherent to their medication regimen when compared to patients with no prior complications.