ANTEPARTUM FETAL EVALUATION - DEVELOPMENT OF A FETAL BIOPHYSICAL PROFILE
ANTEPARTUM FETAL EVALUATION - DEVELOPMENT OF A FETAL BIOPHYSICAL PROFILE
复制标题
DOI：
10.1016/0002-9378(80)90457-3
复制
发表时间：
1980-01-01
影响因子：
9.8
通讯作者：
SIPOS, L
中科院分区：
文献类型：
--
作者：
MANNING, FA;PLATT, LD;SIPOS, L
对216例高危妊娠患者同一观察期内的胎儿生物物理指标(5)、胎儿呼吸、胎动、胎音、定性羊水量及非应激试验进行测定。所有在最后一次观察后一周内交付。以5 min Apgar评分、分娩时胎儿窘迫和围产儿死亡率（RNM）判断个体生物物理变量和变量组合与妊娠结局的关系。对于任何单一测试，假阴性率都很低，并且在测试之间相似，但假阳性率很高（bbb50 %），并且在测试之间差异显著。与任何单一测试相比，组合测试导致假阴性和假阳性率的显着变化。当所有5个变量都被研究时，获得了正常胎儿与受损胎儿最准确的区分。当所有变量均为正常时，PNM取值范围为0；当所有变量均为异常时，PNM取值范围为600/1000。综合胎儿生物物理检查显然是一种比任何单一方法更准确的产前胎儿评估方法。
Fetal biophysical variables (5), fetal breathing movements, fetal movements, fetal tone, qualitative amniotic fluid volume and the nonstress test, were measured in the same observation period in 216 patients with high-risk pregnancies. All delivered within 1 wk of the last observation. The relationship between individual biophysical variables and combinations of variables to the outcome of pregnancy as judged by 5 min Apgar score, fetal distress in labor and perinatal mortality rate (RNM) was determined. For any single test, the false negative rate was low and was similar between tests, but the false positive rate was high (> 50%) and varied significantly between tests. Combining tests resulted in a significant change in both the false negative and false positive rates compared to any single test. The most accurate differentiation of the normal from the compromised fetus was obtained when all 5 variables were studied. The PNM ranged from 0 when all variables were normal to 600/1000 when all were abnormal. Combined fetal biophysical testing is evidently a more accurate method of antepartum fetal evaluation than any single method.