Methylmercury exposure and health effects.
Methylmercury exposure and health effects.
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DOI：
10.3961/jpmph.2012.45.6.353
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发表时间：
2012-11
期刊：
影响因子：
--
通讯作者：
Lee KE
中科院分区：
文献类型：
--
作者：
Hong YS;Kim YM;Lee KE
甲基汞是一种对环境健康有影响的危险物质，因为在一般环境中循环的无机汞会溶解在淡水和海水中，通过食物链浓缩，被人类摄入，从而影响人类健康。最近，人们对甲基汞的毒性、与鱼类和贝类摄入量的相关性以及甲基汞对人类健康影响的长期管理方法产生了很大的兴趣和讨论。长期接触低浓度甲基汞对人体健康的影响仍有争议。尽管不断有人提出和讨论甲基汞对心脏和血管系统、生殖系统和免疫系统造成毒害的可能性，而且也在讨论甲基汞的致癌性，但尚未就接触水平对人类健康的影响得出明确的结论。粮农组织/世卫组织食品添加剂联合专家委员会建议，根据对鱼类和贝类中所含甲基汞的危害性进行的量化评估，为消费者制定额外的鱼类和贝类摄入量建议，但韩国的甲基汞管理尚未跟上这一国际趋势。目前，已知韩国人的甲基汞暴露水平非常高。甲基汞暴露管理的出发点是一般环境中的无机汞，但通过甲基化的食物摄入是主要的暴露源。沿着在一般环境中减少汞的努力，韩国应进行食物摄入管理，以减少人类对甲基汞的暴露。
Methylmercury is a hazardous substance that is of interest with regard to environmental health, as inorganic mercury circulating in the general environment is dissolved into freshwater and seawater, condensed through the food chain, ingested by humans, and consequently affects human health. Recently, there has been much interest and discussion regarding the toxicity of methylmercury, the correlation with fish and shellfish intake, and methods of long-term management of the human health effects of methylmercury. What effects chronic exposure to a low concentration of methylmercury has on human health remains controversial. Although the possibility of methylmercury poisoning the heart and blood vessel system, the reproductive system, and the immune system is continuously raised and discussed, and the carcinogenicity of methylmercury is also under discussion, a clear conclusion regarding the human health effects according to exposure level has not yet been drawn. The Joint FAO/WHO Expert Committee on Food Additives proposed to prepare additional fish and shellfish intake recommendations for consumers based on the quantified evaluation of the hazardousness of methylmercury contained in fish and shellfish, methylmercury management in the Korea has not yet caught up with this international trend. Currently, the methylmercury exposure level of Koreans is known to be very high. The starting point of methylmercury exposure management is inorganic mercury in the general environment, but food intake through methylation is the main exposure source. Along with efforts to reduce mercury in the general environment, food intake management should be undertaken to reduce the human exposure to methylmercury in Korea.