Leisure-Time Physical Activity Reduces Total and Cardiovascular Mortality and Cardiovascular Disease Incidence in Older Adults
Leisure-Time Physical Activity Reduces Total and Cardiovascular Mortality and Cardiovascular Disease Incidence in Older Adults
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DOI：
10.1111/jgs.14694
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发表时间：
2017-03-01
影响因子：
6.3
通讯作者：
Jousilahti, Pekka
中科院分区：
文献类型：
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作者：
Barengo, Noel C.;Antikainen, Riitta;Jousilahti, Pekka
研究目的确定闲暇时间体力活动（LTPA）是否与老年人的全因死亡率、心血管死亡率、心血管疾病（CVD）和中风的发病率独立相关。（中位随访11.8年）。芬兰五个省的研究人员在1997年至2007年期间在芬兰参加基线风险因素调查的65至74岁的男性和女性（N=2，456）.测量研究方案包括一份自我填写的问卷、在研究地点进行的健康检查和用于实验室分析的血样。LTPA分为低、中、高三个级别。死亡率数据来自国家死亡原因登记册和心血管事件数据（冠心病，中风）事件从国家医院出院登记。（年龄、地区、学习年份、性别、吸烟、体重指数、收缩压、血清胆固醇、教育程度、婚姻状况）总死亡率风险（中度：风险比（HR）=0.61，95%置信区间（CI）=0.50-0.74;高度：HR=0.47，95% CI=0.34-0.63，趋势P
ObjectivesTo determine whether leisure-time physical activity (LTPA) is independently associated with all-cause and cardiovascular mortality and with incidence of cardiovascular disease (CVD) and stroke in older adults.DesignPopulation-based cohort study (median follow-up 11.8years).SettingCommunity, five Finnish provinces.ParticipantsMen and women aged 65 to 74 who participated in a baseline risk factor survey between 1997 and 2007 in Finland (N=2,456).MeasurementsThe study protocol included a self-administered questionnaire, health examination at the study site, and blood sample for laboratory analysis. LTPA was classified into three levels: low, moderate, high. Mortality data were obtained from the National Causes of Death Register and data on incident CVD (coronary heart disease, stroke) events from the National Hospital Discharge Register.ResultsMultifactorial-adjusted (age, area, study year, sex, smoking, body mass index, systolic blood pressure, serum cholesterol, education, marital status) risks of total mortality (moderate: hazard ratio (HR)=0.61, 95% confidence interval (CI)=0.50-0.74; high: HR=0.47, 95% CI=0.34-0.63, P for trend