Comparison of Two Questionnaires for Dry Eye Symptom Assessment The Ocular Surface Disease Index and the Symptom Assessment in Dry Eye
Comparison of Two Questionnaires for Dry Eye Symptom Assessment The Ocular Surface Disease Index and the Symptom Assessment in Dry Eye
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DOI：
10.1016/j.ophtha.2015.02.037
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发表时间：
2015-07-01
期刊：
影响因子：
13.7
通讯作者：
Dana, Reza
中科院分区：
文献类型：
--
作者：
Amparo, Francisco;Schaumberg, Debra A.;Dana, Reza
目的：本研究的目的是比较患者报告的干眼病（DED）症状，通过眼表疾病指数（OSDI），一个12项症状频率为基础的问卷，和症状评估的干眼（桑德），2项频率和严重程度为基础的视觉模拟量表进行评估。设计：基于临床的诊断测试评估。参与者：共114例DED患者。方法：在基线和随访时，对患者进行OSDI和桑德问卷调查，以评估DED相关症状。两种问卷评分之间的相关性采用斯皮尔曼系数进行评估，其临床差异采用Bland-Altman分析进行评估。主要结果测量：基线和随访时OSDI和桑德干眼症状评分。结果：在基线访视时，OSDI和桑德问卷评分显著相关（R = 0.64; P < 0.001）。此外，OSDI和桑德评分从基线到随访的变化之间存在显著相关性（R = 0.47; P < 0.001）。分数标准化后的Bland-Altman分析显示，两份问卷的分数之间的差异（偏差）小于2个百分制单位。从桑德问卷收集的数据显示与OSDI的数据具有显著相关性，评分差异可忽略不计，这表明基于桑德视觉模拟量表的问卷有可能为临床医生提供一个简短、快速、和可靠的测量方法。(C)2015年，美国眼科学会。
Purpose: The aim of this study was to compare patient-reported symptoms of dry eye disease (DED) as assessed by the Ocular Surface Disease Index (OSDI), a 12-item symptom frequency-based questionnaire, and the Symptom Assessment iN Dry Eye (SANDE), a 2-item frequency-and severity-based visual analog scale.Design: Clinic-based evaluation of a diagnostic test.Participants: A total of 114 patients with DED.Methods: Patients were administered the OSDI and SANDE questionnaires at baseline and follow-up visits to evaluate DED-related symptoms. The correlations between both questionnaires' scores were evaluated using the Spearman coefficient, and their clinical differences were assessed using Bland-Altman analysis.Main Outcome Measures: Baseline and follow-up visit OSDI and SANDE dry eye symptom scores.Results: At the baseline visit, the OSDI and SANDE questionnaire scores were significantly correlated (R = 0.64; P < 0.001). Moreover, a significant correlation was found between changes in the OSDI and SANDE scores from baseline to follow-up visits (R = 0.47; P < 0.001). A Bland-Altman analysis, after score normalization, revealed a difference (bias) of less than 2 centesimal units between the scores of the 2 questionnaires.Conclusions: Data collected from the SANDE questionnaire showed a significant correlation and negligible score differences with those from the OSDI, suggesting that the SANDE visual analog scale-based questionnaire has the potential to provide clinicians with a short, quick, and reliable measure for DED symptoms. (C) 2015 by the American Academy of Ophthalmology.