Pulse-Driven Magnetoimpedance Sensor Detection of Cardiac Magnetic Activity
Pulse-Driven Magnetoimpedance Sensor Detection of Cardiac Magnetic Activity
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DOI：
10.1371/journal.pone.0025834
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发表时间：
2011-10-12
期刊：
影响因子：
3.7
通讯作者：
Uchiyama, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Nakayama, Shinsuke;Sawamura, Kenta;Uchiyama, Tsuyoshi
本研究旨在建立一种简便的检测心脏生物磁活动的方法。心脏的电活动同时引起磁场。这种磁活动的检测将使得能够进行非接触、非侵入性的评估。我们提高了灵敏度的脉冲驱动磁阻（PMI）传感器，这是用作电子罗盘在移动的手机和作为运动传感器的操作手柄在电脑游戏中，朝皮特斯拉（pT）的水平，并测量人体胸壁表面上的磁场。该传感器检测到的磁场变化与心电图（ECG）的电活动同步。通过将传感器位置平行和/或垂直于胸壁移动20 mm内，磁波的形状在很大程度上改变。第四肋间肌靠近胸骨中央处的磁活动最强。此外，在胸壁和传感器之间距离为15 mm处对磁活动进行平均，证明磁波模拟P波和QRS波群。本研究展示了PMI传感器在检测几个健康受试者心脏磁活动中的应用，并提出了该技术在医学和生物学中的未来应用。
This study sought to establish a convenient method for detecting biomagnetic activity in the heart. Electrical activity of the heart simultaneously induces a magnetic field. Detection of this magnetic activity will enable non-contact, noninvasive evaluation to be made. We improved the sensitivity of a pulse-driven magnetoimpedance (PMI) sensor, which is used as an electric compass in mobile phones and as a motion sensor of the operation handle in computer games, toward a pico-Tesla (pT) level, and measured magnetic fields on the surface of the thoracic wall in humans. The changes in magnetic field detected by this sensor synchronized with the electric activity of the electrocardiogram (ECG). The shape of the magnetic wave was largely altered by shifting the sensor position within 20 mm in parallel and/or perpendicular to the thoracic wall. The magnetic activity was maximal in the 4th intercostals near the center of the sterna. Furthermore, averaging the magnetic activity at 15 mm in the distance between the thoracic wall and the sensor demonstrated magnetic waves mimicking the P wave and QRS complex. The present study shows the application of PMI sensor in detecting cardiac magnetic activity in several healthy subjects, and suggests future applications of this technology in medicine and biology.