Inhibition of herpesvirus and human DNA polymerases by alpha-halogenated phosphonoacetates.
Inhibition of herpesvirus and human DNA polymerases by alpha-halogenated phosphonoacetates.
复制标题
α-卤化膦酰乙酸盐抑制疱疹病毒和人类 DNA 聚合酶。
DOI：
10.1016/0006-2952(87)90618-6
复制
发表时间：
1987
影响因子：
5.8
通讯作者：
Cheng,YC
中科院分区：
文献类型：
--
作者：
McKenna,CE;Khawli,LA;Bapat,A;Harutunian,V;Cheng,YC
MATERIALS AND METHODSGeneral methods and materials. Phosphorus (31P, 109.35 MHz) NMR spectra were obtained on a Bruker WP-270SY spectrometer. Melting points were measured using a Thomas-Hoover capillary melting point apparatus and are uncorrected. Elemental analyses were performed by Galbraith Laboratories.[3H] TTP was purchased from Moravek Biochemicals, Brea, CA. dATP, dCTP, dGTP, TTP, single stranded-and native-DNA cellulose, and calf thymus DNA were obtained from Sigma Biochemicals, St. Louis, MO. DEAE-cellulose and phosphocellulose were products of Whatman Inc., Clifton, NJ. All other chemicals were reagent grade.
