CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer.
CCR 20th anniversary commentary: Preclinical study of proteasome inhibitor bortezomib in head and neck cancer.
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DOI:
10.1158/1078-0432.ccr-14-2550
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发表时间:
2015-03-01
期刊:
影响因子:
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通讯作者:
Van Waes C
中科院分区:
文献类型:
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作者:
Allen CT;Conley B;Sunwoo JB;Van Waes C
In a study published in the May 1, 2001, issue ofClinical Cancer Research, Sunwoo and colleagues provided evidence for proteasome inhibition of NF-κB and tumorigenesis, supporting early-phase clinical trials in solid malignancies of the upper aerodigestive tract. Subsequent clinical studies uncovered a dichotomy of responses in patients with hematopoietic and solid malignancies, and the mechanisms of resistance.Clin Cancer Res; 21(5); 942–3. ©2015 AACR.See related article by Sunwoo et al., Clin Cancer Res 2001;7(5) May 2001;1419–28