Cortisol in hair, body mass index and stress-related measures

Cortisol in hair, body mass index and stress-related measures
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DOI:
10.1016/j.biopsycho.2012.03.010
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发表时间:
2012-07-01
影响因子:
2.6
通讯作者:
Kirschbaum, Clemens
Kirschbaum, Clemens
中科院分区:
医学3区
文献类型:
--
作者:
Stalder, Tobias;Steudte, Susann;Kirschbaum, Clemens

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头发皮质醇浓度(HCC)被认为是反映长期整合皮质醇分泌的指标,并可能为应激相关的内分泌变化提供敏感的标记物。在这里,我们报告了两项独立研究的数据,分别有155名(研究I)和58名参与者(研究II),在这两项研究中,肝癌与不同的应激相关测量和体重指数(BMI)的相关性被调查。在两项研究(研究I:r=.33,p<.001;研究II:r=.42,p=.001)中,一致的证据表明肝细胞癌和体重指数之间存在正相关。另一方面,研究结果未能揭示出可靠的肝细胞癌与心理社会变量的相关性,在研究II中,仅显示与自我报告的社会超负荷呈正相关(r=.29,p=.03),而与其他压力相关措施无关。(C)2012爱思唯尔B.V.保留所有权利。
Hair cortisol concentrations (HCC) are assumed to reflect integrated cortisol secretion over extended periods of time and may provide a sensitive marker for stress-associated endocrine changes. Here, we report data from two independent studies of 155 (study I) and 58 participants (study II) in which HCC associations with different stress-related measures and body mass index (BMI) were investigated. Consistent evidence for positive associations between HCC and BMI was seen across both studies (study I: r = .33, p < .001; study II: r = .42, p = .001). On the other hand, findings failed to reveal reliable HCC associations with psychosocial variables, showing only a positive relationship with self-reported social overload in study II (r = .29, p = .03) but not with other stress-related measures. (C) 2012 Elsevier B.V. All rights reserved.