Evaluation of peripheral artery disease with the TIVITA® Tissue hyperspectral imaging camera system

Evaluation of peripheral artery disease with the TIVITA® Tissue hyperspectral imaging camera system
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DOI:
10.3233/ch-199215
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发表时间:
2019-01-01
影响因子:
2.1
通讯作者:
Weinrich, Malte
Weinrich, Malte
中科院分区:
医学4区
文献类型:
--
作者:
Grambow, Eberhard;Dau, Michael;Weinrich, Malte

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背景技术背景:外周动脉疾病(PAD)的客观、可靠和简便的筛查对于确诊和启动相应的治疗至关重要。因此,一种新的非侵入式高光谱相机目的:假设TIVITA(R)组织的氧合参数与用于检测PAD的已建立的模式相关,并且允许区分具有和不具有PAD的个体。方法:对25名健康年轻人和24名年龄相当的PAD患者和25名非PAD患者的足底内侧动脉血管体进行组织氧合评价。因此,使用TIVITA(R)Tissue测量浅表氧合(StO(2))和近红外(NIR)灌注指数。此外,踝臂指数(ABI),无主诉步行距离和血管生活质量进行了评估,并从所有参与者中获得人口统计学数据。结果:TIVITA(R)组织分析显示,与健康的年轻参与者和无PAD的患者相比,PAD患者的StO(2)和NIR灌注指数显着降低。StO(2)和NIR灌注指数与ABI、无主诉步行距离和血管生活质量scores.CONCLUSIONS呈正相关:总之,这种新的高光谱成像相机在PAD筛查和随访方面具有很大的潜力。
BACKGROUND: Objective, reliable and easy screening for peripheral artery disease (PAD) is essential to confirm the diagnosis and initiate the respective treatment. Therefore, a new non-invasive hyperspectral camera (TIVITA (R) Tissue) was tested in patients with and without PAD.OBJECTIVE: It was hypothesized that the oxygenation parameters of the TIVITA (R) Tissue correlate to established modalities for detection of PAD and allow differentiation between individuals with and without PAD.METHODS: Evaluation of tissue oxygenation was performed in the angiosome of the medial plantar artery in 25 healthy young people and in 24 patients with and 25 patients without PAD in comparable age. Thereby, superficial oxygenation (StO(2)) and near-infrared (NIR) perfusion index were measured with the TIVITA (R) Tissue. Additionally, the ankle-brachial-index (ABI), the complaint free walking distance and the vascular quality of life were assessed and demographic data were obtained from all participants.RESULTS: TIVITA (R) Tissue analysis revealed significantly reduced StO(2) and NIR perfusion index in PAD compared to healthy young participants and patients without PAD. StO(2) and NIR perfusion index positively correlated with ABI, the complaint free walking distance and the vascular quality of life score.CONCLUSIONS: In summary, this new hyperspectral imaging camera bears great potential for PAD screening as well as for follow up.