Alternative stable states in host–phage dynamics
Alternative stable states in host–phage dynamics
复制标题
宿主噬菌体动力学中的替代稳定状态
作者：
J. Weitz;J. Dushoff
噬菌体在自然界中无处不在，但宿主-噬菌体生物学的许多核心方面尚未整合到数学模型中。我们提出了一种新的宿主-噬菌体种群动态模型，该模型解释了宿主接近其承载能力时，噬菌体裂解宿主的能力下降。与现有的捕食者-猎物模型相比，我们发现了一个参数制度，在该制度中，捕食者不能入侵一个主机只有系统，但尽管如此，可以稳定地与主机在较低的密度共存。替代稳定状态的发现表明与观察到的生活史策略的明确联系。此外，我们解决了所提出的模型的一个极限情况下，并表明保守的捕食-食饵类系统不一定会出现人口周期。最后，我们讨论了可能的扩展本模型和方案的实验测试。
Bacteriophage are ubiquitous in nature, yet many central aspects of host–phage biology have not been integrated into mathematical models. We propose a novel model of host–phage population dynamics that accounts for the decreased ability of phages to lyse hosts as hosts approach their carrying capacity. In contrast to existing predator–prey-like models, we find a parameter regime in which phages cannot invade a host-only system but, nonetheless, can stably coexist with hosts at lower densities. The finding of alternative stable states suggests clear linkages with observed life history strategies of phages. In addition, we solve a limiting case of the proposed model and show that conservative predator-prey like systems do not inevitably exhibit population cycles. Finally, we discuss possible extensions of the present model and scenarios for experimental testing.
陆地噬菌体之间广泛的遗传交换。
DOI：
10.1073/pnas.0503074102
发表时间：
2005
影响因子：
11.1
作者：
Silander,OlinK;Weinreich,DanielM;Wright,KevinM;O'Keefe,KaraJ;Rang,CamillaU;Turner,PaulE;Chao,Lin
通讯作者：
Chao,Lin