An unexpected role of a trace amount of water in catalyzing proton transfer in phosphine-catalyzed (3+2) cycloaddition of allenoates and alkenes
An unexpected role of a trace amount of water in catalyzing proton transfer in phosphine-catalyzed (3+2) cycloaddition of allenoates and alkenes
复制标题
微量水在膦催化联烯酸酯和烯烃的 (3 2) 环加成反应中催化质子转移中的意外作用
DOI：
10.1021/ja068215h
复制
发表时间：
2007-03-28
影响因子：
15
通讯作者：
Yu, Zhi-Xiang
中科院分区：
文献类型：
--
作者：
Xia, Yuanzhi;Liang, Yong;Yu, Zhi-Xiang
Through the joint forces of computation and experiment, the detailed mechanism of the Lu phosphine catalyzed (3 + 2) cycloaddition of allenoates and alkenes has been elucidated. The overall potential energy surface of the Lu (3 + 2) reaction has been computed. More importantly, theory and experiment have confirmed that a trace amount of water plays a critical role in assisting the process of [1,2] proton shift in the Lu reaction.
