Quality of life after surgery, external beam irradiation, or brachytherapy for early-stage prostate cancer
Quality of life after surgery, external beam irradiation, or brachytherapy for early-stage prostate cancer
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DOI：
10.1002/cncr.22676
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发表时间：
2007-06-01
期刊：
影响因子：
6.2
通讯作者：
Reiter, Robert E.
中科院分区：
文献类型：
--
作者：
Litwin, Mark S.;Gore, John L.;Reiter, Robert E.
背景临床局限性前列腺癌的主要治疗方法对大多数患者具有等同的癌症控制，但副作用不同。在目前的研究中，作者试图比较最常用的治疗后的健康相关生活质量（HRQOL）结果。共有580名男性在接受根治性前列腺切除术（RP）、外束放射治疗（EBRT）或近距离放射治疗（BT）治疗前和治疗后24个月内完成了医学结局研究简表-36、加州大学洛杉矶分校（UCLA）前列腺癌指数和美国泌尿外科协会症状指数。总体HRQOL似乎不受治疗影响。BT后尿路梗阻和刺激症状较BT多见（P
BACKGROUND. The primary treatments for clinically localized prostate cancer confer equivalent cancer control for most patients but disparate side effects. In the current study, the authors sought to compare health-related quality of life (HRQOL) outcomes after the most commonly used treatments.METHODS. A total of 580 men completed the Medical Outcomes Study Short Form-36, the University of California-Los Angeles (UCLA) Prostate Cancer Index, and the American Urological Association Symptom Index before and through 24 months after treatment with radical prostatectomy (RP), external beam radiation therapy (EBRT), or brachytherapy (BT).RESULTS. General HRQOL did not appear to be affected by treatment. Obstructive and irritative urinary symptoms were more common after BT (P