LIPOSOMES CAN MIMIC VIRUS MEMBRANES

LIPOSOMES CAN MIMIC VIRUS MEMBRANES
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DOI:
10.1038/252161a0
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发表时间:
1974-01-01
期刊:
影响因子:
64.8
通讯作者:
MACDONAL.R
MACDONAL.R
中科院分区:
综合性期刊1区
文献类型:
--
作者:
MARTIN, F;MACDONAL.R

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通过对简单脂质膜的研究,人们对膜渗透性和运输机制有了相当深入的了解。然而,对于膜-膜相互作用的研究,此类模型系统的使用程度要小得多。如果目前关于生物膜具有扩展的脂质双层区域的观点是正确的,那么双层区域很可能参与膜间现象,例如粘附和融合,并且使用简单的脂质膜来模拟这种行为变得合理。
CONSIDERABLE insight into mechanisms of membrane permeability and transport has been obtained from the study of simple lipid membranes. For the study of membrane–membrane interactions, however, such model systems have been used to a much lesser extent. If present ideas that biological membranes possess extended areas of lipid bilayer are correct, then it is probable that bilayer regions are involved in intermembrane phenomena such as adhesion and fusion, and it becomes reasonable to use simple lipid membranes to mimic such behaviour.