Size Threshold Perimetry Performs as Well as Conventional Automated Perimetry With Stimulus Sizes III, V, and VI for Glaucomatous Loss
Size Threshold Perimetry Performs as Well as Conventional Automated Perimetry With Stimulus Sizes III, V, and VI for Glaucomatous Loss
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大小阈值周边测量法与传统的自动周边测量法在刺激大小为 III、V 和 VI 时的青光眼损失效果一样好
DOI：
10.1167/iovs.12-11300
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发表时间：
2013-06-01
影响因子：
4.4
通讯作者：
Johnson, Chris A.
中科院分区：
文献类型：
--
作者：
Wall, Michael;Doyle, Carrie K.;Johnson, Chris A.
目的.认为大的周边刺激对于显示视野缺陷不敏感。为了检验青光眼患者中异常测试位置的总数与总偏差经验概率图没有差异的假设，我们比较了青光眼患者使用尺寸III（0.43度直径）、V（1.72度）和VI（3.44度）测试的结果，以及尺寸阈值视野检查（STP），一种通过改变刺激尺寸来发现阈值的方法。我们从60名年龄匹配的正常人中推导出使用第二次检验的总偏差概率图的规范性限值。我们分析了120名青光眼患者在42个测试常见的非盲点位置的概率图（平均偏差为-9.3 +/- 6.1 dB，范围为-0.2至-31.6）。我们使用单因素重复测量秩方差分析比较了5%水平下的异常测试位置数。我们用平均偏差对结果进行分层。测试中异常测试位置的数量存在统计学显著差异：III，28.5; V，29.7; VI，27.0;和STP，28.8，P = 0.001; Tukey成对比较对于V号和VI号之间以及STP和VI号之间的评估具有统计学显著性。当按平均偏差分层时，对于轻度视力丧失，尺寸V最敏感，其次是STP;尺寸VI的敏感性略低。尺寸V和STP为检测轻度至中度青光眼提供了有利的刺激方法。VI号对青光眼的敏感性稍低，有轻度损失。
PURPOSE. It is thought that large perimetric stimuli are insensitive for demonstrating visual field defects. To test the hypothesis that there is no difference in the total number of abnormal test locations with total deviation empiric probability plots in glaucoma patients, we compared results of glaucoma patients tested with sizes III (0.43 degrees diameter), V (1.72 degrees), and VI (3.44 degrees), and size threshold perimetry (STP), a method that finds threshold by changing stimulus size.METHODS. We derived normative limits for total deviation probability plots using the second test from 60 age-matched normals. We analyzed the probability plots of 120 glaucoma patients (mean deviation was -9.3 +/- 6.1 dB with a range of -0.2 to -31.6) at the 42 nonblind spot locations common to the tests. We compared the number of abnormal test locations at the 5% level among the tests using one-way repeated measures ANOVA on ranks. We stratified the results by mean deviation.RESULTS. There was a statistically significant difference in the number of abnormal test locations among the tests: III, 28.5; V, 29.7; VI, 27.0; and STP, 28.8, P = 0.001; Tukey pairwise comparisons were statistically significant for the assessments between sizes V and VI and between STP and size VI. When stratifying by mean deviation, with mild visual loss, size V was most sensitive, followed by STP; size VI appeared slightly less sensitive.CONCLUSIONS. Size V and STP provide favorable stimulus methodology for detection of mild to moderate glaucoma. Size VI appears slightly less sensitive for glaucoma with mild loss.