PERITONEAL-FLUID VOLUME, 17BETA-ESTRADIOL AND PROGESTERONE CONCENTRATIONS IN WOMEN WITH ENDOMETRIOSIS AND OR LUTEINIZED UNRUPTURED FOLLICLE SYNDROME

PERITONEAL-FLUID VOLUME, 17BETA-ESTRADIOL AND PROGESTERONE CONCENTRATIONS IN WOMEN WITH ENDOMETRIOSIS AND OR LUTEINIZED UNRUPTURED FOLLICLE SYNDROME
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DOI:
10.1159/000299260
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发表时间:
1983-01-01
影响因子:
2.1
通讯作者:
THOMAS, K
THOMAS, K
中科院分区:
医学4区
文献类型:
--
作者:
DONNEZ, J;LANGEROCK, S;THOMAS, K

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报告了子宫内膜异位症(n = 80)和黄体化未破裂卵泡(LUF)综合征(n = 32)女性的排卵口、雌二醇(17 - β .-雌二醇)和黄体酮的体积和浓度的数据,并与先前报道的正常排卵女性的数据进行了比较。在子宫内膜异位症患者中,排卵口较少,在中度和重度子宫内膜异位症患者中差异显著。在黄体期,子宫内膜异位症患者的腹膜液量没有统计学差异。正常妇女和轻度子宫内膜异位症妇女腹膜液中雌二醇和黄体酮水平无显著差异。中度(期20-22天)和重度子宫内膜异位症(期14-19天和20-22天)妇女腹膜液中类固醇浓度较低,这可能解释了这些妇女(腹膜类固醇缺乏)不孕症发生率高的原因。在第14-19天和第20-22天,LUF综合征妇女的腹膜类固醇浓度非常低。显然,腹膜液黄体酮测定有助于诊断LUF综合征。
Data on the presence of an ovulation ostium and the volume and the concentrations of estradiol (17.beta.-estradiol) and progesterone in women with endometriosis (n = 80) and women with luteinized unruptured follicle (LUF) syndrome (n = 32) are reported and compared with data obtained from normal ovulatory women, previously reported. In women with endometriosis, less ovulation ostia were observed, the difference being significant in moderate and severe endometriosis. During the luteal phase, no statistical difference was found in the amount of peritoneal fluid of women with endometriosis. Estradiol and progesterone levels in the peritoneal fluid of normal women and women with mild endometriosis were not significantly different. Lower steroid concentrations found in peritoneal fluid of women with moderate (phase days 20-22) and severe endometriosis (phase days 14-19 and 20-22) may explain the high incidence of infertility reported in these women (peritoneal steroids deficiency). During the phases days 14-19 and 20-22, very low peritoneal steroid concentrations were found in women with LUF syndrome. Apparently progesterone assay in peritoneal fluid is an aid to diagnose the LUF syndrome.