Preservation of pregnancy in a patient with a stage IIIB ovarian epithelial carcinoma diagnosed at 22 weeks of gestation and treated with initial chemotherapy: case report and literature review.
Preservation of pregnancy in a patient with a stage IIIB ovarian epithelial carcinoma diagnosed at 22 weeks of gestation and treated with initial chemotherapy: case report and literature review.
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妊娠 22 周诊断为 IIIB 期卵巢上皮癌并接受初始化疗的患者的妊娠保留：病例报告和文献综述。
DOI：
10.1016/j.ygyno.2004.05.030
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发表时间：
2004
影响因子：
4.7
通讯作者：
P. Morice
中科院分区：
文献类型：
--
作者：
O. Picone;C. Lhommé;M. Tournaire;P. Pautier;S. Camatte;M. Vacher;D. Castaigne;P. Morice
背景报告一例成功治疗的FIGO III期卵巢类胶质癌，在妊娠22周时被诊断为妊娠期卵巢类胶质癌，并在保留妊娠的同时进行初始化疗。她生了一个健康的孩子。同时，进行了根治性子宫切除术、网膜切除术、盆腔和腹主动脉旁淋巴结切除术以及腹膜切除术。手术切除完整（无肉眼可见残留病变）。在组织学检查中，发现了持续性疾病的痕迹。患者在根治性手术后接受了7个疗程的化疗（卡铂+紫杉醇方案）。经过18个月的后续治疗后，病人仍然完全缓解和儿童的发展是normal.ConclusionChemotherapy在妊娠期间与保存胎儿可以考虑，并应讨论在怀孕中期诊断为上皮性卵巢癌（EOC）的情况下。
BackgroundTo report a case of successful management of a FIGO stage III endometrioid carcinoma of the ovary diagnosed during pregnancy at 22 weeks of gestation and treated with initial chemotherapy while preserving the pregnancy.CaseThe patient underwent a planned cesarean section at 34 weeks after two courses of carboplatin. She delivered a healthy baby. At the same time, a radical hysterectomy, omentectomy, pelvic and paraaortic lymphadenectomies and peritonectomies were carried out. The surgical resection was complete (no macroscopic residual disease). During histologic examination, traces of persistent disease were found. The patient underwent seven postoperative courses of chemotherapy (carboplatin + paclitaxel regimen) after radical surgery. After 18 months of follow-up posttreatment, the patient remains in complete remission and the child's development is normal.ConclusionChemotherapy during pregnancy with preservation of the fetus could be considered and should be discussed in case of epithelial ovarian cancer (EOC) diagnosed during the second trimester of the pregnancy.
妊娠期间晚期上皮性卵巢癌。
DOI：
--
发表时间：
2007
期刊：
International Journal of Clinical Oncology. 12
影响因子：
--
作者：
Ishioka;S;Hatashi;T;Endo;T;et. al.
通讯作者：
et. al.