Lipid-Lowering Effects of Curcumin in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Lipid-Lowering Effects of Curcumin in Patients with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
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DOI：
10.1002/ptr.5197
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发表时间：
2014-12-01
影响因子：
7.2
通讯作者：
Ueng, Kwo-Chang
中科院分区：
文献类型：
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作者：
Yang, Yi-Sun;Su, Ying-Fang;Ueng, Kwo-Chang
姜黄素提取物对降脂效果的人体研究尚未完全调查，结果也有争议。本研究测试了连续12周每天服用姜黄素提取物对代谢综合征患者体重、葡萄糖和脂质谱的影响。65例患者随机分为两组；33例患者服用姜黄素提取物胶囊（630mg，每日三次），32例患者服用安慰剂胶囊，每日三次，连续12周。在姜黄素提取物消耗12周后，高密度脂蛋白胆固醇（HDL-C）水平从40.96 +/- 8.59显著增加到43.76 +/- 2.79mg/dL (p
Human studies of curcumin extract on lipid-lowering effect have not been completely investigated and have had controversy results. This study tested the effect of daily curcumin extract for 12weeks on weight, glucose, and lipid profiles in patients with metabolic syndrome. Sixty-five patients were randomized into two groups; 33 patients taking curcumin extract capsule (630mg thrice daily) and 32 patients taking a placebo capsule thrice daily for 12weeks. At 12weeks after the curcumin extract consumption, the level of high-density lipoprotein cholesterol (HDL-C) significantly increased from 40.96 +/- 8.59 to 43.76 +/- 2.79mg/dL (p