SPARX, a new environment for Cryo-EM image processing

SPARX, a new environment for Cryo-EM image processing
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DOI:
10.1016/j.jsb.2006.07.003
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发表时间:
2007-01-01
影响因子:
3
通讯作者:
Ludtke, Steven J.
Ludtke, Steven J.
中科院分区:
生物学3区
文献类型:
--
作者:
Hohn, Michael;Tang, Grant;Ludtke, Steven J.

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SPARX(用于分辨率扩展的单颗粒分析)是一种新的图像处理环境,特别侧重于透射电子显微镜(TEM)结构测定。它包括一个图形用户界面,该界面提供了一个具有新颖数据/流程基础设施的完整图形编程环境,一个执行特定TEM相关计算任务的大量Python脚本库,以及一个基本的C++图像处理函数核心库。此外,SPARX依赖于EMAN2库和cctbx(来自PHENIX的开源计算晶体学库)。该系统的设计使得未来纳入其他图像处理库成为一项简单的任务。SPARX基础设施能够智能地处理中间值的保留,即使是在诸如循环和函数调用等编程结构内部的值。SPARX及其所有依赖项可供学术使用且免费,并提供完整的源代码。(c)2006爱思唯尔公司。保留所有权利。
SPARX (single particle analysis for resolution extension) is a new image processing environment with a particular emphasis on transmission electron microscopy (TEM) Structure determination. It includes a graphical User interface that provides a complete graphical programming environment with a novel data/process-flow infrastructure, an extensive library of Python scripts that perform specific TEM-related computational tasks, and a core library of fundamental C++ image processing functions. In addition, SPARX relies on the EMAN2 library and cctbx, the open-source computational crystallography library from PHENIX. The design of the system is Such that future inclusion of other image processing libraries is a straightforward task. The SPARX infrastructure intelligently handles retention of intermediate values, even those inside programming Structures Such as loops and function calls. SPARX and all dependencies are free for academic use and available with complete source. (c) 2006 Elsevier Inc. All rights reserved.