CHARACTERIZATION OF MOUSE LIVER-CELL LINE FL83B
CHARACTERIZATION OF MOUSE LIVER-CELL LINE FL83B
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DOI：
10.1016/0014-4827(73)90089-x
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发表时间：
1973-01-01
影响因子：
3.7
通讯作者：
LEVY, RI
中科院分区：
文献类型：
--
作者：
BRESLOW, JL;SLOAN, HR;LEVY, RI
先前报道的小鼠肝细胞系FL83B在光镜和电镜下的外观、染色体组成和分泌各种血清蛋白的能力方面得到了更完整的表征。这些细胞与实质肝细胞具有许多惊人的形态相似性。染色体分析显示细胞已转化。这些细胞在完全化学定义的培养基中生长的能力，明确证明了至少12种小鼠血清蛋白的合成，包括白蛋白和高密度脂蛋白。
The previously reported mouse liver cell line FL83B has been characterized more completely with respect to its light and electron microscopic appearance, chromosomal composition, and ability to secrete various serum proteins. These cells bear many striking morphological similarities to parenchymal liver cells. Chromosomal analysis showed that the cells were transformed. The ability of these cells to grow in a completely chemically defined medium permitted the unequivocal demonstration of the synthesis of at least 12 mouse serum proteins including albumin and high density lipoprotein.