Evaluation of two single-factor models of metabolic syndrome: a confirmatory factor analysis for an adult population in Beijing.
Evaluation of two single-factor models of metabolic syndrome: a confirmatory factor analysis for an adult population in Beijing.
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DOI：
10.1186/1476-511x-12-61
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发表时间：
2013-05-02
影响因子：
4.5
通讯作者：
Guo X
中科院分区：
文献类型：
--
作者：
Huo D;Wang W;Li X;Gao Q;Wu L;Luo Y;Wang Y;Zhang P;Guo X
代谢综合征在中国的患病率很高，而且还在增加。这种紊乱的原因尚待完全了解。几项验证性因素分析的研究已经进行了调查，在一些种族以外的疾病的核心，在其他研究中，他们已经取得了良好的模型拟合。本研究采用验证性因素分析方法，对中国人群代谢综合征潜在因素结构的两个单因素模型进行评价和比较。结果显示，在7，472名中国人的样本中，模型1（与腰围、甘油三酯/高密度脂蛋白-胆固醇比值、空腹血糖和平均动脉压）产生良好的健身水平（SRMR < 0.08，CFI > 0.96，RMSEA < 0.10）;和模型2（与腰围、甘油三酯、空腹血糖和收缩压）在18-34岁和60岁以上的男性以及除35-59岁男性外的所有女性中拟合良好（RMSEA = 0.142）。相比之下，模型2在所有年龄组的女性和18-34岁和60岁以上的男性中显示出更好的拟合（具有相对较大的GFI和较小的AIC，BIC，CAIC和EVIC）;模型1在35至59岁之间的男性中具有更好的拟合。本研究提示，腰围、甘油三酯、空腹血糖、收缩压与代谢综合征的单因素模型在北京地区各年龄组女性和中青年男性中均成立。以腰围、甘油三酯/高密度脂蛋白胆固醇比值、空腹血糖和平均动脉压为指标的模型适合中年男性。
Prevalence of metabolic syndrome is high and increasing in China. The causation of this disorder is, yet, to be fully understood. Several studies with confirmatory factor analysis have been performed to investigate the core of the disease in some races other than Chinese, and amongst the other studies, they have yielded a sound model fit. This study was to evaluate and compare two single-factor models of the underlying factor structure of metabolic syndrome in a Chinese population using confirmatory factor analysis. Findings showed that in a Chinese sample of 7,472 individuals, Model 1 (with waist circumference, triglycerides/HDL-C ratio, fasting plasma glucose and mean artery pressure) yielded good level of fitness (SRMR < 0.08, CFI > 0.96 and RMSEA < 0.10) in men and women of all age groups; and Model 2 (with waist circumference, triglycerides, fasting plasma glucose and systolic blood pressure) fitted well in men aged 18–34 and over 60 and in all women, except in men of 35–59 (RMSEA = 0.142). In comparison, Model 2 were shown to be better fit (with relative larger GFI and smaller AIC, BIC, CAIC, and EVIC) in women of all age groups and in men of 18–34 and over 60 years old; Model 1 had a better fit in men between 35 and 59. This study suggests that the single-factor model of metabolic syndrome with waist circumference, triglycerides, fasting plasma glucose and systolic blood pressure are plausible in women of all age groups and young and senior men in Beijing. The model with waist circumference, triglycerides/HDL-C ratio, fasting plasma glucose and mean artery pressure fits middle-aged men.