Cortical feed-forward networks for binding different streams of sensory information

Cortical feed-forward networks for binding different streams of sensory information
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DOI:
10.1038/nn1798
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发表时间:
2006-12-01
影响因子:
25
通讯作者:
Stuart, Greg J.
Stuart, Greg J.
中科院分区:
医学1区
文献类型:
--
作者:
Kampa, Bjorn M.;Letzkus, Johannes J.;Stuart, Greg J.

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不同的感觉信息流被传输到大脑皮层,在那里它们被合并为一个感知,这一过程通常被称为“捆绑”。利用大鼠大脑皮层第2/3层和第5层锥体神经元三联体的记录,我们发现第5层内的特定子网络接受来自不同第2/3层子网络的输入。这种皮质微结构可能代表了一种机制,使大脑皮层的主要输出(第5层)能够绑定感觉刺激的不同特征。
Different streams of sensory information are transmitted to the cortex where they are merged into a percept in a process often termed 'binding.' Using recordings from triplets of rat cortical layer 2/3 and layer 5 pyramidal neurons, we show that specific subnetworks within layer 5 receive input from different layer 2/3 subnetworks. This cortical microarchitecture may represent a mechanism that enables the main output of the cortex (layer 5) to bind different features of a sensory stimulus.