Relationship between metabolic syndrome and periodontitis in 80-year-old Japanese subjects.
Relationship between metabolic syndrome and periodontitis in 80-year-old Japanese subjects.
复制标题
80 岁日本受试者代谢综合征与牙周炎的关系。
DOI：
10.1111/jre.12190
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发表时间：
2015
影响因子：
3.5
通讯作者：
Hideo Miyazaki
中科院分区：
文献类型：
--
作者：
Kumiko Minagawa;Masanori Iwasaki;Hiroshi Ogawa;A. Yoshihara;Hideo Miyazaki
背景与目的
代谢综合征（MetS）和牙周炎之间的潜在显着的关联已在最近的研究报告，但是，有有限的数据，他们在非常老的关联。这项横断面研究的目的是调查80岁的日本受试者之间的MetS和牙周炎之间的关联。
材料和方法
受试者是234名80岁的日本人，他们于2008年6月在日本新泻市参加了健康和牙周检查，并被分为三组：（i）严重牙周炎：有6个或更多临床附着水平≥ 6 mm的邻间部位和3个或更多探测囊袋深度（PPD）≥ 5 mm的邻间部位（不在同一颗牙齿上）（n = 19）;（ii）中度牙周炎：具有6个或更多个临床附着水平≥ 4 mm的邻间位点或6个或更多个PPD ≥ 5 mm的邻间位点（不在同一颗牙齿上）（n = 162）;和（iii）无或轻度牙周炎：既不是“中度”牙周炎也不是“重度”牙周炎（n = 53）。使用日本MetS诊断指南的修改标准定义MetS。有序逻辑回归模型被用来评估代谢综合征和牙周炎之间的关联。考虑了性别、收入、教育、吸烟状况、牙科就诊模式、刷牙频率、运动习惯和饮食能量和食物摄入量的调整。
结果
总体而言，57人（24.4%）被诊断为患有MetS。MetS与牙周炎的存在和严重程度相关（粗比值比= 2.24，95%置信区间= 1.14-4.41）。在多变量调整后，这种关联仍然具有统计学意义（调整后的比值比= 2.10，95%置信区间= 1.03-4.28）。
结论
我们的研究结果提供了证据的MetS和牙周炎之间的关联在老年日本。
BACKGROUND AND OBJECTIVE
Potentially significant associations between metabolic syndrome (MetS) and periodontitis have been reported in recent studies; however, there are limited data on their association in the very old. The aim of this cross-sectional study was to investigate the association between MetS and periodontitis among 80-year-old Japanese subjects.
MATERIAL AND METHODS
The subjects were 234 Japanese aged 80 years old who participated in a health and periodontal examination in June 2008 in Niigata city, Japan, and were classified into three groups: (i) severe periodontitis: having six or more interproximal sites with clinical attachment level ≥ 6 mm and three or more interproximal sites with probing pocket depth (PPD) ≥ 5 mm (not on the same tooth) (n = 19); (ii) moderate periodontitis: having six or more interproximal sites with clinical attachment level ≥ 4 mm or six or more interproximal sites with PPD ≥ 5 mm (not on the same tooth) (n = 162); and (iii) no or mild periodontitis: neither "moderate" nor "severe" periodontitis (n = 53). MetS was defined using the modified criteria of the guidelines for the diagnosis of MetS in Japan. An ordinal logistic regression model was used to evaluate the association between MetS and periodontitis. Adjustments for gender, income, education, smoking status, dental visiting patterns, brushing frequency, exercise habits and dietary energy and food intake were considered.
RESULTS
Overall, 57 individuals (24.4%) were diagnosed as having MetS. MetS was associated with the presence and severity of periodontitis (crude odds ratio = 2.24, 95% confidence interval = 1.14-4.41). This association remained statistically significant after multivariate adjustments (adjusted odds ratio = 2.10, 95% confidence interval = 1.03-4.28).
CONCLUSION
Our findings provide evidence of an association between MetS and periodontitis in elderly Japanese.