The etiologic spectrum of head and neck squamous cell carcinoma in young patients.
The etiologic spectrum of head and neck squamous cell carcinoma in young patients.
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年轻患者头颈部鳞状细胞癌的病因谱
DOI：
10.18632/oncotarget.11265
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发表时间：
2016-10-04
期刊：
影响因子：
--
通讯作者：
Tang YL
中科院分区：
文献类型：
--
作者：
Liu X;Gao XL;Liang XH;Tang YL
头颈部鳞状细胞癌（Head and Neck Squamous Cell Carcinoma，HNSCC）占头颈部恶性肿瘤的80%以上，每年在世界范围内造成数千人死亡。尽管大多数患者年龄在45岁以上，头颈部肿瘤的发病率呈下降趋势，但可怕的是，45岁以下患者的发病率却在稳步上升。因此，对儿童和青壮年HNSCC危险因素的病原学研究具有重要意义。这篇综述概述了45岁以下患者的HNSCC，特别是口腔/口咽鳞状细胞癌的病因谱。
Head and neck squamous cell carcinoma (HNSCC), accounting for more than 80% in head and neck malignancies, kills thousands of people a year in the world. Despite most of the patients are more than 45, and the occurrences of head and neck cancer shows a decreasing trend; however, horribly, the incidences of the patients under 45 years old is steadily increasing. Hence, it's of vital importance to get more pathogen information about risk factors of HNSCC in children and young adults. This review outlines the etiologic spectrum of HNSCC, especially oral/oropharyngeal squamous cell carcinoma, in patients under 45 years of age.