Cryosurgical monitoring using bioimpedance measurements - A feasibility study for electrical impedance tomography
Cryosurgical monitoring using bioimpedance measurements - A feasibility study for electrical impedance tomography
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DOI：
10.1109/10.871411
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发表时间：
2000-10-01
影响因子：
4.6
通讯作者：
Rubinsky, B
中科院分区：
文献类型：
--
作者：
Otten, DM;Rubinsky, B
冷冻手术治疗肿瘤的有效性高度依赖于对冷冻程度的了解，因此严重依赖于实时成像技术进行监测。电阻抗断层扫描（EIT），它利用组织阻抗变化来构建图像，是非常适合冷冻手术，因为冷冻组织的阻抗远高于未冷冻组织，在这项研究中，我们探讨冷冻手术监测作为一个以前未调查的应用EIT。生物阻抗测量的可行性，以检测冰前的传播证明了冷冻平面组织样本一维，而测量阻抗沿着线性阵列。实验结果相比，毫不逊色，一个简单的有限元模型设计提供一个电场可视化工具。
The effectiveness of cryosurgery in treating tumors is highly dependent on knowledge of freezing extent, and therefore relies heavily on real-time imaging techniques for monitoring. Electrical impedance tomography (EIT), which utilizes tissue impedance variation to construct an image, is very well suited to cryosurgery since frozen tissue impedance is much higher than that of unfrozen tissue, In this study, we explore cryosurgical monitoring as a previously uninvestigated application for EIT. The feasibility of bio-impedance measurements to detect ice front propagation is demonstrated by freezing planar tissue samples one-dimensionally while measuring impedance along a linear array. The experimental results compare favorably to a simple finite element model designed to provide an electrical field visualization tool.