Potentiometric Determination of Trace Amounts of Amantadine Using a Modified Carbon-Paste Electrode
Potentiometric Determination of Trace Amounts of Amantadine Using a Modified Carbon-Paste Electrode
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DOI：
10.2116/analsci.25.1227
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发表时间：
2009-10-01
影响因子：
1.6
通讯作者：
Maghooli, R.
中科院分区：
文献类型：
--
作者：
Jalali, F.;Maghooli, R.
本文报道了一种灵敏、选择性测定金刚烷胺的化学修饰碳糊电极。β-环糊精用作改性剂。在25 ℃下，对于浓度范围为6.3 x 10（-10）- 7.1 x 10（-7）M的金刚烷胺，电极显示出51.0 +/- 1.0 mV decade（-1）的亚能斯特响应。使用0.02 M乙酸盐缓冲液将最佳pH值保持在4.5。该电极的检测限为6.3 × 10（-10）M金刚烷胺。电极响应非常迅速（
A chemically modified carbon-paste electrode has been described for the sensitive and selective determination of amantadine. beta-Cyclodextrin was used as modifier. The electrode shows a sub-Nernstian response of 51.0 +/- 1.0 mV decade(-1) for amantadine in the concentration range of 6.3 x 10(-10) - 7.1 x 10(-7) M at 25 degrees C. The optimum pH value was maintained at 4.5 using a 0.02 M acetate buffer. The limit of detection of the electrode was 6.3 x 10(-1)0 M of amantadine. The electrode responded very rapidly (