Corticospinal excitability modulation in resting digit muscles during cyclical movement of the digits of the ipsilateral limb.
Corticospinal excitability modulation in resting digit muscles during cyclical movement of the digits of the ipsilateral limb.
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DOI：
10.3389/fnhum.2015.00607
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发表时间：
2015
影响因子：
2.9
通讯作者：
Kanosue K
中科院分区：
文献类型：
--
作者：
Muraoka T;Sakamoto M;Mizuguchi N;Nakagawa K;Kanosue K
我们研究了同侧肢体的手指运动如何调制静息手指肌肉的皮质脊髓兴奋性。受试者进行右脚趾或手指的周期性伸展-屈曲运动。为了确定是否皮质脊髓兴奋性的休息手指肌肉调制的基础上的运动方向或动作之间的耦合同侧手指，右前臂保持在旋前或旋后的位置。在运动过程中，由经颅磁刺激（TMS）引起的运动诱发电位（MEP）从静止的右手手指伸肌和屈肌，或脚趾伸肌和屈肌。对于手指和脚趾肌肉，独立的前臂位置，MEP幅度的屈肌是更大的同侧手指屈曲相比，伸展，MEP幅度的伸肌是更大的同侧手指伸展相比，屈曲。一个例外是，MEP振幅的脚趾屈肌与旋后前臂之间没有不同的手指伸展和屈曲。这些发现表明，手指运动调节皮质脊髓兴奋性的同侧肢体的手指，使相同的行动是首选。我们的研究结果为更好地理解同侧肢体之间的神经相互作用提供了证据，因此可能有助于中风或不完全脊髓损伤后的神经康复。
We investigated how corticospinal excitability of the resting digit muscles was modulated by the digit movement in the ipsilateral limb. Subjects performed cyclical extension-flexion movements of either the right toes or fingers. To determine whether corticospinal excitability of the resting digit muscles was modulated on the basis of movement direction or action coupling between ipsilateral digits, the right forearm was maintained in either the pronated or supinated position. During the movement, the motor evoked potential (MEP) elicited by transcranial magnetic stimulation (TMS) was measured from either the resting right finger extensor and flexor, or toe extensor and flexor. For both finger and toe muscles, independent of forearm position, MEP amplitude of the flexor was greater during ipsilateral digit flexion as compared to extension, and MEP amplitude of the extensor was greater during ipsilateral digit extension as compared to flexion. An exception was that MEP amplitude of the toe flexor with the supinated forearm did not differ between during finger extension and flexion. These findings suggest that digit movement modulates corticospinal excitability of the digits of the ipsilateral limb such that the same action is preferred. Our results provide evidence for a better understanding of neural interactions between ipsilateral limbs, and may thus contribute to neurorehabilitation after a stroke or incomplete spinal cord injury.