Clinical Applications of FDG PET and PET/CT in Head and Neck Cancer.
Clinical Applications of FDG PET and PET/CT in Head and Neck Cancer.
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DOI：
10.1155/2009/208725
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发表时间：
2009
影响因子：
--
通讯作者：
Schwaiger M
中科院分区：
文献类型：
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作者：
Al-Ibraheem A;Buck A;Krause BJ;Scheidhauer K;Schwaiger M
18F-FDG PET在头颈癌的诊断和治疗计划中发挥着越来越重要的作用。PET/CT杂交技术促进了头颈部肿瘤分子成像领域的发展。考虑到复杂的解剖结构和可变的生理FDG摄取模式，这种模式与头颈部区域特别相关。绝大多数18F-FDG PET和PET/CT在头颈部癌症中的应用与头颈部鳞状细胞癌有关。18F-FDG PET和PET/CT在头颈部肿瘤中的临床应用包括：远处转移的诊断、同步第二原发癌的鉴别、原发不明的癌的检测、残留或复发的检测。新兴的应用是精确描绘肿瘤体积，用于放射治疗计划，监测治疗，并提供预后信息。18F-FDG PET/CT在N0疾病中的临床作用有限，这与其他影像学检查结果一致。MRI通常用于T分期，随着PET/CT、MRI和多层螺旋CT的快速发展，关于区域淋巴结分期的首选成像方式的讨论也越来越激烈。本文综述了近年来关于18F-FDG PET和PET/CT在头颈癌诊断中的研究进展。
18F-FDG PET plays an increasing role in diagnosis and management planning of head and neck cancer. Hybrid PET/CT has promoted the field of molecular imaging in head and neck cancer. This modality is particular relevant in the head and neck region, given the complex anatomy and variable physiologic FDG uptake patterns. The vast majority of 18F-FDG PET and PET/CT applications in head and neck cancer related to head and neck squamous cell carcinoma. Clinical applications of 18F-FDG PET and PET/CT in head and neck cancer include diagnosis of distant metastases, identification of synchronous 2nd primaries, detection of carcinoma of unknown primary and detection of residual or recurrent disease. Emerging applications are precise delineation of the tumor volume for radiation treatment planning, monitoring treatment, and providing prognostic information. The clinical role of 18F-FDG PET/CT in N0 disease is limited which is in line with findings of other imaging modalities. MRI is usually used for T staging with an intense discussion concerning the preferable imaging modality for regional lymph node staging as PET/CT, MRI, and multi-slice spiral CT are all improving rapidly. Is this review, we summarize recent literature on 18F-FDG PET and PET/CT imaging of head and neck cancer.