Image quality improvements in C-Arm CT (CACT) for liver oncology applications: preliminary study in rabbits.
Image quality improvements in C-Arm CT (CACT) for liver oncology applications: preliminary study in rabbits.
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DOI：
10.3109/13645706.2013.788028
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发表时间：
2013-09
期刊：
影响因子：
--
通讯作者：
Geschwind JF
中科院分区：
文献类型：
--
作者：
Tacher V;Bhagat N;Rao PV;Lin M;Schäfer D;Noordhoek N;Eshuis P;Radaelli A;Liapi E;Grass M;Geschwind JF
C形臂CT（CACT）是肝脏肿瘤治疗中的一种新型成像模式，可在术中采集3D图像。CACT已被用于通过改善病变检测、避免非靶向栓塞和允许更有选择性地输送药物来增强肝脏的动脉内治疗。然而，该技术的局限性之一是由呼吸运动产生的图像伪影。在本初步研究中确定可提高CACT图像质量（IQ）的图像采集、运动补偿和高分辨率3D重建的改进。本研究使用3只成年雄性新西兰白色家兔。首先，对照兔被用来选择最佳的X射线采集成像协议，然后两只兔子被植入肝脏肿瘤，以进一步开发3D图像重建和运动补偿算法。使用低80 kVp方案获得最佳IQ，运动补偿重建具有高分辨率和快速采集速度（60 fps，5 s/扫描和312张图像）。通过以下方式提高IQ：（1）缩短采集时间，（2）应用运动补偿重建，以及（3）高分辨率3D重建。这项研究的结果可以应用于未来的动物研究，最终可以转化为临床环境。
C-Arm CT (CACT) is a new imaging modality in liver oncology therapy that allows for the acquisition of 3D images intra-procedurally. CACT has been used to enhance intra-arterial therapies for the liver by improving lesion detection, avoiding non-target embolization, and allowing for more selective delivery of agents. However, one of the limitations of this technology is image artifacts created by respiratory motion. To determine in this preliminary study improvements in image acquisition, motion compensation, and high resolution 3D reconstruction that can improve CACT image quality (IQ). Three adult male New Zealand white rabbits were used for this study. First, a control rabbit was used to select the best x-ray acquisition imaging protocol and then two rabbits were implanted with liver tumor to further develop 3D image reconstruction and motion compensation algorithms. The best IQ was obtained using the low 80 kVp protocol with motion compensated reconstruction with high resolution and fast acquisition speed (60 fps, 5 s/scan, and 312 images). IQ improved by: (1) decreasing acquisition time, (2) applying motion-compensated reconstruction, and (3) high resolution 3D reconstruction. The findings of this study can be applied to future animal studies and eventually could be translated into the clinical environment.
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影响因子：
3.8
作者：
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通讯作者：
Johnson, G. Allan
DOI：
10.1016/j.jvir.2008.02.018
发表时间：
2008-06-01
影响因子：
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作者：
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发表时间：
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影响因子：
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作者：
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作者：
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