Postnatal Development of the Structure of the Peripheral Vestibular System of the Gerbil

Postnatal Development of the Structure of the Peripheral Vestibular System of the Gerbil
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沙鼠周围前庭系统结构的产后发育

DOI:
10.1267/ahc.31.33
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发表时间:
1998
影响因子:
2.4
通讯作者:
A. Seto‐ohshima
A. Seto‐ohshima
中科院分区:
生物学4区
文献类型:
--
作者:
N. Kawamura;Muneyuki Ito;A. Seto‐ohshima

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为获得前庭电刺激的拓扑学信息,对沙土鼠出生后外周前庭系统及其周围成分的发育进行了研究。出生后第1天,前庭周围神经已经到达前庭器。前庭中枢神经向后延伸,与前后轴呈锐角进入脑干。在发育过程中,前庭神经节逐渐向尾侧移位,沿着前庭神经和位于腹侧的面神经,到出生后30天,与前后轴的角度增加到近90°。前庭神经节前部与面神经接触,前庭神经节后部与耳蜗神经接触。这些区域被认为不适合电刺激,因为刺激面神经或耳蜗神经的风险很高,类似于成人的那些区域。这些结果以及观察到的外半规管的直径几乎保持不变,表明我们在成年动物中使用的前庭电刺激技术显然也是年轻动物的良好选择。
Postnatal development of the peripheral vestibular system and surrounding components in the gerbil was studied to obtain topological information for electrical vestibular stimulation. At postnatal day 1, the peripheral vestibular nerve had already reached the vestibular apparatus. The central vestibular nerve extended posteriorly to enter the brainstem at a sharp angle to anterior-posterior axis. During development, the vestibular ganglion was progressively displaced caudally, along with the vestibular nerve and the ventrally located facial nerve, increasing the angle to the anterior-posterior axis to nearly 90° by postnatal day 30. Contact between the anterior part of the vestibular ganglion and the facial nerve, and that between the posterior part of the ganglion and the cochlear nerve were observed at all ages. These regions were considered unsuitable for electrical stimulation because of the high risk of stimulating the facial or cochlear nerve, similar to those regions in the adult. These results as well as the observation that the diameter of the lateral semicircular canal remained nearly constant showed that the technique we used for electrical vestibular stimulation in adult animals was apparently a good choice in younger animals as well.
DOI: --
发表时间: 1991
期刊: Critical reviews in neurobiology
影响因子: --
作者:
P. Jobe;P. K. Mishra;N. Ludvig;J. Dailey
通讯作者: P. Jobe;P. K. Mishra;N. Ludvig;J. Dailey