Global burden of noncommunicable disease attributable to high body mass index in 195 countries and territories, 1990-2017
Global burden of noncommunicable disease attributable to high body mass index in 195 countries and territories, 1990-2017
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DOI：
10.1007/s12020-020-02352-y
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发表时间：
2020-06-02
期刊：
影响因子：
3.7
通讯作者：
Shan, Peng-Fei
中科院分区：
文献类型：
--
作者：
Lin, Xiling;Xu, Yufeng;Shan, Peng-Fei
高身体质量指数（BMI）导致的非传染性疾病（NCDs）负担日益增加，这既是一种威胁，也是干预的机会。估计与高bmi相关的非传染性疾病的全球最新趋势及其与社会经济地位的关系，可以促进战略干预并为进一步研究提供信息。方法：这项全球疾病负担研究从2017年GBD研究中提取了与高bmi相关的非传染性疾病相关的死亡和残疾调整生命年（DALYs）的全球、地区和国家数据。二级分析按年份、年龄、性别、具体死亡原因和伤残调整生命年进行。2017年社会人口指数（SDI）被用作国家社会经济地位的指标。分析年龄标准化死亡率或伤残调整生命年率与社会经济地位之间的关系。2017年，全球有470万例非传染性疾病死亡和1.477亿DALYs与高BMI有关，预计到2025年将有550万例死亡和1.769亿DALYs。在全球范围内，高bmi相关负担呈上升趋势，男性总体受影响更大。在不同的地理和社会经济区域，高bmi相关疾病负担的趋势和程度有很大差异。具体而言，低、中、高SDI国家与较高的负担相关。2017年，高BMI导致DALYs的前三大原因是缺血性心脏病、中风和糖尿病。结论高bmi相关的非传染性疾病负担正在恶化，特别是在发展中国家。我们的研究结果可能会提高公众对减少高BMI引起的疾病负担的干预意识。
Purpose The increasing burden of noncommunicable diseases (NCDs) attributable to high body mass index (BMI) represents both a threat and an opportunity for intervention. Estimates of the global latest trend of high BMI-related NCDs and its association with socioeconomic status can facilitate strategic intervention and inform further research. Methods This global burden of disease study extracted global, regional, and national data on death and disability-adjusted life years (DALYs) attributable to high BMI-related NCDs from the GBD Study 2017. Secondary analyses were performed by year, age, sex, and specific causes of death and DALYs. The 2017 Socio-demographic Index (SDI) was used as an indicator of national socioeconomic status. The association between age-standardized death or DALYs rate and socioeconomic status were analyzed. Results Worldwide, 4.7 million deaths and 147.7 million DALYs of NCDs were related to high BMI in 2017, with a projection to 5.5 million deaths and 176.9 million DALYs in 2025. Globally, high BMI-related burden showed an increasing trend with males being more heavily impacted overall. The trend and magnitude of high BMI-related disease burden varied substantially in different geographical and socioeconomic regions. Specifically, the low-middle, middle, and high-middle SDI countries were associated with a higher burden. The leading three causes of DALYs attributable to high BMI in 2017 were ischemic heart diseases, stroke, and diabetes mellitus. Conclusions High BMI-related burden of NCDs is worsening, particularly in developing countries. Our findings may enhance public awareness of interventions to reduce the diseases burden caused by high BMI.