Control of synchronization in models of hydrodynamically coupled motile cilia
Control of synchronization in models of hydrodynamically coupled motile cilia
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DOI：
10.1038/s42005-018-0031-6
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发表时间：
2018-06-27
影响因子：
5.5
通讯作者：
Cicuta, Pietro
中科院分区：
文献类型：
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作者：
Maestro, Armando;Bruot, Nicolas;Cicuta, Pietro
在许多生物体中，多个运动纤毛协调它们的跳动以促进游泳或驱动表面流。需要简单的模型来定量地了解这种协调是如何实现的;纤毛内和纤毛之间有两种尺度的现象，并且都具有复杂的非线性和非热效应。我们在这里研究一个模型，这是易于处理的分析，并可以实现光学捕获胶体粒子：纤毛内属性是粗粒化的参数选择驱动粒子周围封闭的局部轨道。根据这些有效参数，可以实现各种锁相稳态。我们推导出一个理论，其中包括两个机制的同步：运动的灵活性沿着预定义的轨道和调制的驱动力。我们表明，适度调整纤毛节拍性能，可以实现生物学，结果在流体动力学耦合所产生的集体运动的巨大变化。
In many organisms, multiple motile cilia coordinate their beating to facilitate swimming or driving of surface flows. Simple models are required to gain a quantitative understanding of how such coordination is achieved; there are two scales of phenomena, within and between cilia, and both host complex non-linear and non-thermal effects. We study here a model that is tractable analytically and can be realized by optical trapping colloidal particles: intra-cilia properties are coarse grained into the parameters chosen to drive particles around closed local orbits. Depending on these effective parameters a variety of phase-locked steady states can be achieved. We derive a theory that includes two mechanisms for synchronization: the flexibility of the motion along the predefined orbit and the modulation of the driving force. We show that modest tuning of the cilia beat properties, as could be achieved biologically, results in dramatic changes in the collective motion arising from hydrodynamic coupling.