The impact of impulsivity on cocaine use and retention in treatment
The impact of impulsivity on cocaine use and retention in treatment
复制标题
DOI：
10.1016/s0740-5472(01)00202-1
复制
发表时间：
2001-12-01
影响因子：
3.9
通讯作者：
Grabowski, J
中科院分区：
文献类型：
--
作者：
Moeller, FG;Dougherty, DM;Grabowski, J
为了确定冲动是否与药物使用的严重程度和治疗结果有关，50名可卡因依赖受试者接受了当前可卡因使用严重程度和Barratt冲动量表（BIS-11）的基线测量。这项研究的假设是，冲动和可卡因使用严重程度之间存在显着相关性。正如预测的那样，BIS-11总分与自我报告的平均每日可卡因使用以及可卡因戒断症状之间存在显著相关性。35名患者的一个子集进行了为期12周的双盲安慰剂对照试验丁螺环酮和组治疗。基线冲动性高的受试者在研究中的停留时间明显短于基线冲动性低的受试者。这项研究表明，冲动是可卡因使用和治疗保留的一个重要预测因素，并建议在可卡因依赖治疗中需要针对冲动。(C)2002年爱思唯尔科技有限公司All rights reserved.
To determine whether impulsivity was related to severity of drug use and treatment outcome, 50 cocaine dependent subjects underwent baseline measures of severity of current cocaine use and the Barratt Impulsiveness Scale (BIS-11). The hypothesis of the study was that there would be a significant correlation between impulsivity and cocaine use severity. As predicted, there was a significant correlation between BIS-11 total scores and self-reported average daily cocaine use as well as cocaine withdrawal symptoms. A subset of 35 patients underwent a 12-week double-blind placebo controlled trial of buspirone and group therapy. Subjects with high baseline impulsivity remained in the study a significantly shorter period than did subjects with lower baseline impulsivity. This study shows that impulsivity is a significant predictor of cocaine use and treatment retention, and suggests the need for targeting impulsivity in cocaine dependence treatment. (C) 2002 Elsevier Science Inc. All rights reserved.