Gastric Cancer Epidemiology and Risk Factors
Gastric Cancer Epidemiology and Risk Factors
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DOI：
10.1016/j.gtc.2013.01.003
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发表时间：
2013-06-01
影响因子：
3.7
通讯作者：
Plummer, Martyn
中科院分区：
文献类型：
--
作者：
de Martel, Catherine;Forman, David;Plummer, Martyn
胃癌是世界上主要的恶性肿瘤之一。本文总结了目前对该疾病的全球负担、其地理变化和时间趋势的认识。概述了已知的危险因素，包括遗传、饮食和行为，但重点关注幽门螺杆菌感染作为非贲门性胃癌最重要的因素。当数据和文献允许时，我们区分贲门和非贲门。子站点，因为现在很明显，这两个解剖位置呈现出截然不同且有时相反的流行病学特征。
Gastric cancer is one of the major malignancies in the world. This article summarizes the current understanding of the worldwide burden of this disease, its geographic variation, and temporal trends. An overview is presented of known risk factors, including genetic, dietary, and behavioral, but focuses on Helicobacter pylori infection as the most important factor in noncardia gastric cancer. When the data and the literature allow, we distinguish between cardia and noncardia. sub-sites, as it is now clear that these two anatomic locations present distinct and sometimes opposite epidemiological characteristics.