Superspreading SARS events, Beijing, 2003.
Superspreading SARS events, Beijing, 2003.
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DOI:
10.3201/eid1002.030732
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发表时间:
2004-02
影响因子:
11.8
通讯作者:
Schuchat A
中科院分区:
文献类型:
--
作者:
Shen Z;Ning F;Zhou W;He X;Lin C;Chin DP;Zhu Z;Schuchat A
Superspreading events were pivotal in the global spread of severe acute respiratory syndrome (SARS). We investigated superspreading in one transmission chain early in Beijing’s epidemic. Superspreading was defined as transmission of SARS to at least eight contacts. An index patient with onset of SARS 2 months after hospital admission was the source of four generations of transmission to 76 case-patients, including 12 healthcare workers and several hospital visitors. Four (5%) case circumstances met the superspreading definition. Superspreading appeared to be associated with older age (mean 56 vs. 44 years), case fatality (75% vs. 16%, p = 0.02, Fisher exact test), number of close contacts (36 vs. 0.37) and attack rate among close contacts (43% vs. 18.5%, p < 0.025). Delayed recognition of SARS in a hospitalized patient permitted transmission to patients, visitors, and healthcare workers. Older age and number of contacts merit investigation in future studies of superspreading.
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影响因子:
5
作者:
CHEN, RT;GOLDBAUM, GM;ORENSTEIN, WA
通讯作者:
ORENSTEIN, WA
影响因子:
5
作者:
MARKS, JS;SERDULA, MK;WIEBENGA, NH
通讯作者:
WIEBENGA, NH
DOI:
10.1016/s0140-6736(03)13412-5
发表时间:
2003-05-24
期刊:
Lancet (London, England)
影响因子:
--
作者:
Peiris JS;Chu CM;Cheng VC;Chan KS;Hung IF;Poon LL;Law KI;Tang BS;Hon TY;Chan CS;Chan KH;Ng JS;Zheng BJ;Ng WL;Lai RW;Guan Y;Yuen KY;HKU/UCH SARS Study Group
通讯作者:
HKU/UCH SARS Study Group
影响因子:
158.5
作者:
Poutanen, SM;Low, DE;McGeer, AJ
通讯作者:
McGeer, AJ
影响因子:
11.8
作者:
Liang W;Zhu Z;Guo J;Liu Z;Zhou W;Chin DP;Schuchat A;Beijing Joint SARS Expert Group
通讯作者:
Beijing Joint SARS Expert Group