Association of increased carotid intima-media thickness with the extent of coronary artery disease

Association of increased carotid intima-media thickness with the extent of coronary artery disease
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DOI:
10.1136/hrt.2003.025080
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发表时间:
2004-11-01
期刊:
影响因子:
5.7
通讯作者:
Konieczynska, M
Konieczynska, M
中科院分区:
医学1区
文献类型:
--
作者:
Kablak-Ziembicka, A;Tracz, W;Konieczynska, M

文献摘要

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目的:探讨颈动脉内膜中层厚度(IMT)与冠状动脉病变程度的关系;(B)IMT是否是冠状动脉粥样硬化的预测指标。同时存在的严重颅外动脉粥样硬化的患者与CAD.Methods:冠状动脉造影和颈动脉超声评价进行了连续558例(438名男子),平均(SD)年龄为58.8(9.2)岁,怀疑CAD。在两个颈动脉测量平均IMT,并表示为平均聚集值。结果:IMT与进展性CAD有显著相关性(P < 0.05),IMT与进展性CAD无显著相关性(P > 0.05),IMT与进展性CAD无显著相关性(P > 0.05)。
Objective: To investigate (a) the relation between intima-media thickness (IMT) in carotid arteries and the extent of coronary artery disease (CAD); and (b) whether IMT is predictive of coronary atherosclerosis. The coexistence of severe extracranial atherosclerosis in patients with CAD was also analysed.Methods: Coronary angiography and carotid ultrasound evaluation were performed in 558 consecutive patients (438 men), with a mean (SD) age of 58.8 (9.2) years and suspected CAD. Mean IMT was measured at both carotid arteries and expressed as the mean aggregate value. The relation between IMT and severity of CAD was determined.Results: A significant correlation between mean IMT and advancing CAD (p