Solvent-Free Synthesis of High-Purity Sucrose Fatty Acid Monoesters and a Comparison of Their Properties with Those of Their Commercial Counterparts
Solvent-Free Synthesis of High-Purity Sucrose Fatty Acid Monoesters and a Comparison of Their Properties with Those of Their Commercial Counterparts
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DOI：
10.1021/acsfoodscitech.1c00185
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发表时间：
2021-10-15
期刊：
影响因子：
--
通讯作者：
Lan, Ping
中科院分区：
文献类型：
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作者：
Xie, Meng-Fei;White, Lorenzo, V;Lan, Ping
大多数市售的蔗糖酯使用需要挥发性有机化合物作为溶剂的合成方案制备。这导致高制造成本、对环境有害的生产过程和具有残留毒性的产品。虽然无溶剂方案可以解决这些问题，但它们通常导致最终产品中单酯含量不足，从而降低了整个产品混合物的市场价值。因此，我们现在报告一个实用的合成协议，提供高纯度的单硬脂酸蔗糖酯在无溶剂条件下。我们还描述了一种有效的超高效收敛色谱-质谱法分析合成的单酯。在优化的条件下，我们的产品混合物的蔗糖单酯组分为74.6重量%，因此与目前市场上最好的商业制剂相当。对无溶剂衍生材料的乳化性能的评价表明，在某些情况下，这些材料上级其商业对应物。因此，这里报道的无溶剂方案代表了目前工业上采用的潜在污染的蔗糖酯生产技术的经济上有吸引力和环境友好的替代方案。
Most commercially available sucrose esters are prepared using synthetic regimes that require volatile organic compounds as solvents. This results in high manufacturing costs, environmentally deleterious production processes, and products possessing residual toxicities. While solvent-free protocols can address these issues, they often lead to an inadequate monoester content in the final product and thereby lower the market value of the overall product mixture. Accordingly, we now report a practical synthetic protocol that delivers high-purity monostearate sucrose esters under solvent-free conditions. We also describe an effective ultraperformance convergence chromatography-mass spectrometric method for analyzing the synthesized monoesters. Under optimized conditions, the sucrose monoester component of our product mixture is 74.6 wt % and thus comparable to those of the best commercial preparations currently on the market. Evaluation of the emulsifying properties of the solvent-free-derived materials established that, in some cases, these were superior to their commercial counterparts. As such, the solvent-free protocol reported here represents both an economically attractive and environmentally friendly alternative to the potentially polluting sucrose ester production techniques currently employed by industry.