Exploitation of the complement system by Leishmania promastigotes

Exploitation of the complement system by Leishmania promastigotes
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DOI:
10.1016/0169-4758(96)10067-3
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发表时间:
1996-11-01
期刊:
PARASITOLOGY TODAY
影响因子:
--
通讯作者:
Mosser, DM
Mosser, DM
中科院分区:
其他
文献类型:
--
作者:
Brittingham, A;Mosser, DM

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补体长期以来被认为是宿主防御细胞外病原体的重要组成部分。大卫莫瑟和安德鲁Brittingham在这里描述了利什曼原虫属,单核吞噬细胞的细胞内病原体,如何利用补体的调理和趋化作用在哺乳动物宿主中启动感染。
Complement has long been acknowledged as an important component of host defense to extracellular pathogens. David Mosser and Andrew Brittingham here describe how Leishmania spp, intracellular pathogens of mononuclear phagocytes, exploit the opsonic and chemotactic effects of complement to initiate infection in the mammalian host.