THE ACTION POTENTIALS OF THE STOMACH
THE ACTION POTENTIALS OF THE STOMACH
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DOI：
10.1152/ajplegacy.1945.144.5.693
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发表时间：
1945-01-01
影响因子：
--
通讯作者：
BOZLER, E
中科院分区：
文献类型：
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作者：
BOZLER, E
用一种新型的微型示差甘汞电极记录了狗、猫和豚鼠暴露胃的动作电位。在狗身上，伴随着每一次收缩波的微分电位与心脏的电位一致，只是复合波的持续时间更长。因此，该曲线的波被命名为R波、S波和T波。一次电击就会导致过早的收缩，随后会出现类似心脏反应的长时间停顿。单相势是由微分势通过图形积分得到的。在狗身上，它主要表现为一段持续的负电期，就像在心肌中一样，但在猫和豚鼠身上，尖峰电位叠加在持续的电位上。结果表明，如果将内脏肌纤维视为独立的单位，内脏肌的电位是不能解释的。胃的活动与心脏的活动以及其他观察到的惊人的相似之处，可以解释为传导是由于肌肉纤维的合胞排列。
The action potentials of the exposed stomach of the dog, cat and guinea pig were recorded using a new type of differential calomel electrode of very small dimensions. In the dog the differential potential accompanying each wave of contraction agrees with that of the heart, except for the longer duration of the complex. The waves of the curve, therefore, were designated as R, S and T waves. A single electric shock can produce a premature contraction followed by a prolonged pause similar to the response of the heart. The monophasic potential was derived from the differential potential by graphic integration. In the dog it shows chiefly a period of sustained negativity, as in cardiac muscle, but, in the cat and guinea pig, spikes are superimposed on the sustained potential. It is shown that the potentials from visceral muscles cannot be explained if the muscle fibers are considered as being independent units. The striking similarity of the activity of the stomach with that of the heart as well as other observations can be explained on the assumption that conduction is due to a syncytial arrangement of the muscle fibers.