Impact of Depression, Fatigue and Disability on Quality of Life in Chinese Patients with Multiple Sclerosis
Impact of Depression, Fatigue and Disability on Quality of Life in Chinese Patients with Multiple Sclerosis
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DOI：
10.1002/smi.2432
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发表时间：
2013-04-01
影响因子：
4.1
通讯作者：
Li, Kangning
中科院分区：
文献类型：
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作者：
Chen, Kelong;Fan, Yongping;Li, Kangning
本研究旨在调查和分析影响多发性硬化症(MS)患者生活质量的主要因素。对100例MS患者进行QOL(多发性硬化影响量表)、残疾(扩展残疾状态量表)、疲劳(修改后的疲劳影响量表)和抑郁(Beck抑郁问卷)的评估。相关分析表明，生活质量与残疾状况、疲劳、抑郁呈正相关，即残疾、疲劳、抑郁程度越重，生活质量越差。多元线性回归分析表明，扩展残疾状态量表评分和疲劳感对MS患者的躯体生活质量有重要的预测价值。另一方面，抑郁和疲劳对MS患者的心理生活质量有重要的预测价值。MS患者的生活质量受多种因素影响，应加强对患者残疾、疲劳、抑郁的护理。版权所有(C)2012 John Wiley&Sons，Ltd.
The aim of this work is to investigate and analyze the main factors that influence the quality of life (QOL) of multiple sclerosis (MS) patients. The QOL (Multiple Sclerosis Impact Scale), disability (Expanded Disability Status Scale), fatigue (Modified Fatigue Impact Scale) and depression (Beck Depression Inventory) were assessed in 100 MS patients. Correlation analysis shows that QOL is positively correlated with disability status, fatigue and depression, i.e. the more severe the disability, fatigue and depression, the worse the QOL. Multiple linear regression analysis indicated that Expanded Disability Status Scale grade and fatigue have important predictive value on the somatic QOL of MS patients. On the other hand, depression and fatigue have important predictive value on the mental QOL of MS patients. The QOL of MS patients is influenced by various factors, nursing care that focuses on patient disability, fatigue and depression should be strengthened. Copyright (c) 2012 John Wiley & Sons, Ltd.