Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area
Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area
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DOI：
10.1038/nn2070
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发表时间：
2008-04-01
影响因子：
25
通讯作者：
Gold, Joshua I.
中科院分区：
文献类型：
--
作者：
Law, Chi-Tat;Gold, Joshua I.
本研究旨在探讨视觉辨别任务中知觉学习的神经机制。我们训练了两只猴子（Macaca mulatta）来确定视觉运动的方向，同时我们记录了它们的中颞区（MT）和侧顶内区（LIP），中颞区代表用于解决任务的运动信息，侧顶内区代表运动信息转化为扫视选择。在训练过程中，对弱运动信号的行为敏感性的提高伴随着LIP中神经元运动驱动反应的变化，但在MT中没有。LIP变化的时间过程和幅度与整个训练过程中行为敏感性的变化相关。因此，对于这项任务，知觉学习似乎并不涉及感官信息在大脑中如何表现的改进，而是如何解释感官表现以形成指导行为的决定。
This study aimed to identify neural mechanisms that underlie perceptual learning in a visual-discrimination task. We trained two monkeys (Macaca mulatta) to determine the direction of visual motion while we recorded from their middle temporal area (MT), which in trained monkeys represents motion information that is used to solve the task, and lateral intraparietal area (LIP), which represents the transformation of motion information into a saccadic choice. During training, improved behavioral sensitivity to weak motion signals was accompanied by changes in motion-driven responses of neurons in LIP, but not in MT. The time course and magnitude of the changes in LIP correlated with the changes in behavioral sensitivity throughout training. Thus, for this task, perceptual learning does not appear to involve improvements in how sensory information is represented in the brain, but rather how the sensory representation is interpreted to form the decision that guides behavior.