CORONARY VASODILATORY RESPONSE TO A NOVEL PEPTIDE, ADRENOMEDULLIN 2
CORONARY VASODILATORY RESPONSE TO A NOVEL PEPTIDE, ADRENOMEDULLIN 2
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DOI：
10.1111/j.1440-1681.2004.04115.x
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发表时间：
2004-12
影响因子：
2.9
通讯作者：
Yuta Kobayashi;Yingjie Liu;T. Gonda;Y. Takei
中科院分区：
文献类型：
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作者：
Yuta Kobayashi;Yingjie Liu;T. Gonda;Y. Takei
1. 肾上腺髓素- 2 （AM2）是最初在鱼类中发现的一种新型肽，它在结构上与哺乳动物AM或鱼类AM1相关。AM2 cDNA在小鼠、大鼠和人体内的克隆已经成功。本研究分析了合成人AM2在猪离体动脉环制剂中的血管扩张作用。
1. Adrenomedullin‐2 (AM2) is a novel peptide originally found in a fish and it is structurally related to mammalian AM or fish AM1. Cloning of AM2 cDNA in the mouse, rat and human has been successful. In the present study, the vasodilatory effect of synthetic human AM2 was analysed in isolated artery ring preparations of porcine.