EFFECT OF SILVER IONS ON RESPIRATORY-CHAIN OF ESCHERICHIA-COLI
EFFECT OF SILVER IONS ON RESPIRATORY-CHAIN OF ESCHERICHIA-COLI
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DOI：
10.1139/m74-135
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发表时间：
1974-01-01
影响因子：
2.8
通讯作者：
RAINNIE, DJ
中科院分区：
文献类型：
--
作者：
BRAGG, PD;RAINNIE, DJ
银离子对完整的大肠杆菌细胞悬浮液氧化葡萄糖、甘油、富马酸、琥珀酸、D-乳酸和L-乳酸及内源底物有抑制作用。银离子与呼吸链在两个水平上发生反应。对抑制最敏感的部位位于b-细胞色素和细胞色素2之间。第二个水平的抑制位于呼吸链的NADH和琥珀酸脱氢酶区域，位于黄素成分的底物一侧。
Silver ions inhibited the oxidation of glucose, glycerol, fumarate, succinate,D- andL-lactate, and endogenous substrates by intact cell suspensions ofEscherichia coli. Silver ions reacted with the respiratory chain at two levels. The site most sensitive to inhibition was located between theb-cytochromes and cytochromea2. The second level of inhibition was in the NADH and succinate dehydrogenase regions of the respiratory chain, and was situated on the substrate side of the flavin components.