Determination and correlation of the solubility of myricetin in ethanol and water mixtures from 288.15 to 323.15K
Determination and correlation of the solubility of myricetin in ethanol and water mixtures from 288.15 to 323.15K
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288.15 至 323.15K 乙醇和水混合物中杨梅素溶解度的测定和相关性
DOI：
10.1080/00319104.2016.1163560
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发表时间：
2017-01-01
影响因子：
1.2
通讯作者：
Zhang, Jiye
中科院分区：
文献类型：
--
作者：
Cai, Shaona;Zhang, Peipei;Zhang, Jiye
采用平衡法在288.15 ~ 323.15K温度范围内，在乙醇-水二元溶剂体系中测定了杨梅素（MY）的溶解度，并用紫外分光光度法在375 nm处测定了MY的溶解度。用简化的普适方程（理想模型）、修正的Apelblat方程、Jouyban-Acree方程对溶解度实验值进行了关联。修正的Apelblat模型更适合于预测MY在乙醇-水二元溶剂体系中的溶解度数据。通过Van 't霍夫和Gibbs−Helmholtz方程计算MY的溶解焓和熵。结果表明，二元体系的溶解过程强烈依赖于溶剂组成和温度，该过程是吸热和熵驱动的。图形摘要
ABSTRACT The solubility of myricetin (MY) is very important in regard to its extraction and purification, which was performed by an equilibrium method in the binary solvent system of ethanol and water in the temperature range 288.15 ~ 323.15 K and was determined by ultraviolet (UV-Vis) spectrophotometry at 375 nm. The experimental solubility values were correlated by four mathematical equations: a simplified universal equation (ideal model), modified Apelblat equation, equation and Jouyban–Acree equation. The modified Apelblat model is more suitable for predicting the solubility data of MY in the binary solvent system of ethanol and water at this experimental temperature range. The dissolution enthalpy and entropy of MY were evaluated by the Van’t Hoff and Gibbs−Helmholtz equations. The results illustrate that the dissolution process in binary system solvent mixtures is strongly dependent on solvent composition and temperature, and this process was endothermic and entropy driven. GRAPHICAL ABSTRACT