ALCOHOL AND MORTALITY - HONOLULU HEART-STUDY
ALCOHOL AND MORTALITY - HONOLULU HEART-STUDY
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DOI：
10.1016/0002-9343(80)90350-2
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发表时间：
1980-01-01
影响因子：
5.9
通讯作者：
PALESCH, Y
中科院分区：
文献类型：
--
作者：
BLACKWELDER, WC;YANO, K;PALESCH, Y
以前的研究表明，在檀香山，饮用酒精饮料的日本男性比不饮用酒精饮料的日本男性患冠心病的可能性更小，而且他们喝得越多（每天约60毫升），患冠心病的风险就越低。在这份关于同一批人的报告中，我们发现冠心病的死亡率也存在同样的关系，但癌症和中风的死亡率则相反。喝酒的人比不喝酒的人更容易死于这些原因，而且他们喝得越多，死亡的风险就越大。饮酒量相对较大的男性比其他男性更容易死于肝硬化。总死亡率的曲线是U形的，风险最低的是每天摄入1-10毫升乙醇的男性。即使在如此低的消费水平下，死于癌症或中风的风险也高于不饮酒者。对于这一日本男性人群，饮酒似乎对死亡率有一些好处和一些危害，而好处或危害取决于所考虑的死亡原因。
It has been shown previously that coronary heart disease was less likely to develop in Japanese men in Honolulu who drank alcoholic beverages than in those who abstained, and that the more they drank (up to about 60 ml/day of ethanol) the lower the risk. In this report on the same men, it is shown that the same sort of relation holds for mortality from coronary heart disease but that the reverse is true for death from cancer and from stroke. Men who drank were more likely to die from these causes than those who abstained, and the more they drank the greater the risk of death. Men who drank relatively large amounts were more likely to die from cirrhosis of the liver than other men. The resultant curve for total mortality is u-shaped, the lowest risk being for men who consumed from 1-10 ml/day of ethanol. Even at that low level of consumption, the risk of death from cancer or stroke was greater than it was for nondrinkers. For this population of Japanese men, alcohol consumption appears to have some benefits and some hazards with regard to mortality, and the benefit or hazard depends on which cause of death is being considered.