Age at onset of generalized anxiety disorder in older adults
Age at onset of generalized anxiety disorder in older adults
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DOI：
10.1176/appi.ajgp.13.1.23
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发表时间：
2005-01-01
影响因子：
7.2
通讯作者：
Wetherell, JL
中科院分区：
文献类型：
--
作者：
Le Roux, H;Gatz, M;Wetherell, JL
目的：探讨老年广泛性焦虑症（GAD）的发病年龄分布及其相关因素。方法：作者研究了67例老年广泛性焦虑症患者的发病年龄分布。他们将症状早发者（50岁之前）与迟发者（50岁之后）的人口统计变量以及精神病理学和健康相关生活质量指标进行了比较。结果如下：发病年龄呈双峰分布，57%报告早发，43%报告晚发。早发症状的患者有更高的精神病合并症和精神药物使用率，更严重的担忧。晚发症状的患者报告更多的功能限制，由于身体问题，结论：虽然大多数老年GAD患者报告发病在儿童或青春期，几乎一半的发展障碍在晚年。早期GAD发病的老年人似乎有一个更严重的过程，其特征是病理性的担忧，比那些晚发病。角色障碍可能是老年广泛性焦虑症发病的危险因素。
Objective: The authors explored the distribution and correlates of age-at-onset of late-life generalized anxiety disorder (GAD). Methods: Authors examined the distribution of age at onset in a sample of 67 older adults with GAD recruited for a psychotherapy study. They compared those with an early onset of symptoms (before age 50) to those with a late onset (after 50) on demographic variables and measures of psychopathology and health-related quality of life. Results: There was a bimodal distribution of age at onset, with 57% reporting early onset and 43% reporting a late onset Patients with an early onset of symptoms had a higher rate of psychiatric comorbidity and psychotropic medication use and more severe worry. Patients with a late onset Of symptoms reported more functional limitations due to physical problems, Conclusions: Although most older GAD patients report an onset in childhood or adolescence, almost half develop the disorder in late life. Older adults with an early onset of GAD appear to have a more severe course, characterized by pathological worry, than those with a later onset. Role disability may be a risk factor for onset of GAD in late life.