Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments.
Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments.
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DOI：
10.1109/tuffc.2022.3220568
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发表时间：
2022-12
影响因子：
3.6
通讯作者：
Zhou, Qifa
中科院分区：
文献类型：
--
作者：
Lu, Gengxi;Qian, Xuejun;Gong, Chen;Ji, Jie;Thomas, Biju B.;Humayun, Mark S.;Zhou, Qifa
关键词：
超声神经调节是一种新兴技术。大量的努力已经致力于研究非侵入性超声视网膜刺激的可行性。最近的研究表明，超声波可以激活健康和退化视网膜中的神经元。具体来说，高频超声可以引起局部神经元的反应，并在视觉回路中产生模式。在这篇综述中，我们概括了超声视网膜刺激的试点研究，将其与其他神经调节技术进行比较，并讨论其优点和局限性。还概述了利用高频超声开发非侵入性视网膜假体的机遇和挑战。
Ultrasound neuromodulation is an emerging technology. A significant amount of effort has been devoted to investigating the feasibility of non-invasive ultrasound retinal stimulation. Recent studies have shown that ultrasound can activate neurons in healthy and degenerated retinas. Specifically, high-frequency ultrasound can evoke localized neuron responses and generate patterns in visual circuits. In this review, we recapitulate pilot studies on ultrasound retinal stimulation, compare it with other neuromodulation technologies, and discuss its advantages and limitations. An overview of the opportunities and challenges to develop a non-invasive retinal prosthesis using high-frequency ultrasound is also provided.