Gamma ray inactivation of some animal viruses.
Gamma ray inactivation of some animal viruses.
复制标题
伽马射线灭活某些动物病毒。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
A. Girard
中科院分区：
文献类型：
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作者：
F. C. Thomas;A. G. Davies;G. Dulac;N. Willis;G. Papp;A. Girard
在Gamma Cell 220（Atomic Energy of Canada Limited）中对20份动物病毒样本（包括12个科的14种不同病毒）进行不同剂量的60 Co源伽马辐照，以确定致死剂量水平。在整个灭活过程中，剂量响应呈线性。D10值，即将感染性降低1个log10所需的剂量，范围为小于0.20 Megarads至约0.55 Megarads。靶大小（病毒体核心）与D10值之间不存在完全的负相关。
Twenty samples of animal viruses comprising 14 different viruses in 12 families were subjected to varying doses of gamma irradiation from a 60Co source in a Gamma Cell 220 (Atomic Energy of Canada Limited) to determine lethal dose levels. The dose responses appeared linear throughout inactivation. The D10 values, that is the dose necessary to reduce infectivity by one log10, ranged from less than 0.20 Megarads to approximately 0.55 Megarads. There was not a complete inverse correlation between the target size (virion core) and the D10 value.